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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
136
Publications avec texte intégral
Open Access
53 %
Mots clés
Cell culture model
Fibrosis
RNA splicing
Duchenne muscular dystrophy
Myotonic dystrophy mouse models
Acetylcholinesterase knockout mouse
DMPK
DM1
Expression
Gene editing
Astrocytes
Myotonic Dystrophy Type 1
CRISPR/Cas9
Heart failure
MBNL
ARN
Myotonic dystrophy type 1
Mice
Oligodendrocyte
Quantitative microdialysis
Central nervous system
Aging
Maximal force
Gene Therapy
Autophagy
Oligodendrocytes
Knockout
Skeletal muscle
Male
Antisense oligonucleotides
Therapy
Acute coronary syndrome
Glial cells
Endurance training
Muscle
GSK3
Transgenic mouse model
Thérapie génique
Brain
Cytoskeleton
Antisense oligonucleotide
Brain dysfunction
RNA biology
Myotonic Dystrophy type 1
Dystrophie myotonique
Cell penetrating peptide
Cardiac muscle
Muscular dystrophy
Animals
Myotonic Dystrophy
Mouse model
PCR
Myostatin
RNA interference
AAV
Centronuclear myopathy
Trinucleotide Repeat Expansion
Astrocyte
Cell model
Glucocorticoid-receptor
CONGENITAL MYATHENIC SYNDROME
PacBio
BIOLOGIE MOLECULAIRE
Genotype phenotype correlation
Glutamate
Transgenic mouse
KNOCKOUT MICE
Exercice
Long read sequencing
Intermediate filament
Gene therapy
ACETYLCHOLINESTERASE
GABA
CTG repeat instability
Neuron
Motoneuron
Desmin
Dynamin 2
Acetylcholinesterase deficiency
Humans
CTG repeats
Exercise
Dystrophie Myotonique
Hypoxia
In vivo
Diaphragm
Mouse models
Heart
Alternative splicing
Glucocorticoids
Myelin
Dystrophin
Transcriptomics
CTG repeat contractions
Dilated cardiomyopathy
DMSXL mice
CMS
Trinucleotide repeat expansion
Myotonic dystrophy
CRISPRi